Saw palmetto (Serenoa repens, SP) is the most expensive oil source of the pharmaceutical and healthfood market, and its high cost and recurrent shortages have spurred the development of designer blends of fatty acids to mimic its phytochemical profile and fraudulently comply with the current authentication assays. To detect this adulteration, the combined use of isotopic fingerprint and omic analysis has been investigated, using Principal Component Analysis (PCA) to handle the complex databases generated by these techniques and to identify the possible source of the adulterants. Surprisingly, the presence of fatty acids of animal origin turned out to be widespread in commercial samples of saw palmetto oil.

Perini, M.; Paolini, M.; Camin, F.; Appendino, G.; Vitulo, F.; De Combarieu, E.; Sardone, N.; Martinelli, E.M.; Pace, R. (2018). Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts. FITOTERAPIA, 127: 15-19. doi: 10.1016/j.fitote.2018.04.011 handle: http://hdl.handle.net/10449/52421

Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts

Perini, M.
Primo
;
Paolini, M.;Camin, F.;
2018-01-01

Abstract

Saw palmetto (Serenoa repens, SP) is the most expensive oil source of the pharmaceutical and healthfood market, and its high cost and recurrent shortages have spurred the development of designer blends of fatty acids to mimic its phytochemical profile and fraudulently comply with the current authentication assays. To detect this adulteration, the combined use of isotopic fingerprint and omic analysis has been investigated, using Principal Component Analysis (PCA) to handle the complex databases generated by these techniques and to identify the possible source of the adulterants. Surprisingly, the presence of fatty acids of animal origin turned out to be widespread in commercial samples of saw palmetto oil.
Serenoa repens
Adulteration
Stable isotope analysis
Principal component analysis
NMR
Lipids
Settore CHIM/10 - CHIMICA DEGLI ALIMENTI
2018
Perini, M.; Paolini, M.; Camin, F.; Appendino, G.; Vitulo, F.; De Combarieu, E.; Sardone, N.; Martinelli, E.M.; Pace, R. (2018). Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts. FITOTERAPIA, 127: 15-19. doi: 10.1016/j.fitote.2018.04.011 handle: http://hdl.handle.net/10449/52421
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