Failure to effectively prove cause and effect between taking probiotics and improvements in recognised markers of disease has greatly hindered the acceptability of probiotic health claims. • One reason for this may be poor probiotic selection. Probiotic strains have not always been selected on the basis of specific health related mechanisms. • Examples of probiotics first selected for bile salt hydrolase activities or gamma-aminobutyric acid (GABA) production are proving exceptions however, and are showing that rational design of probiotic strains capable of modulating host physiological function is possible. • This presentation will discuss the merits of probiotic reverse engineering, selecting probiotic strains with very specific phenotypes capable altering target mammalian physiological processes.
|Citation:||Tuohy, K.M. (2017). Probiotic reverse engineering: choose your mechanism first then your strain. In: 4th Microbiome R&D and Business collaboration Forum, Amsterdam, April 3-4, 2017. handle: http://hdl.handle.net/10449/46186|
|Organization unit:||Department of Food Quality and Nutrition # CRI|
|Title:||Probiotic reverse engineering: choose your mechanism first then your strain|
|Scientific Disciplinary Area:||Settore AGR/15 - Scienze E Tecnologie Alimentari|
|Appears in Collections:||03 - Conference object|
Files in This Item:
|Amsterdam conference April 3 2017 MRAD17-PBC17_Agenda.pdf||N/A||Non specificato||Open AccessView/Open|