Ljungan virus (LV) is a picornavirus originally isolated from Swedish bank voles (Myodes glareolus) in 1998. The association of LV with human disease has been debated ever since, but fundamental data on the ecology of the virus are still lacking. Here we present results of the first intensive study on the prevalence of LV in bank voles trapped in Fennoscandia (Sweden and Finland) from 2009–2012 as determined by PCR. Using an LV-specific RT-PCR, LV was detected in the liver of 73 out of 452 (16.2%) individuals and in 13 out of 17 sampling sites across Sweden and Finland (mean per site prevalence 16%, SE 3%, range 0–50%). We found more infected animals in autumn compared to spring, and lighter and heavier individuals had a higher prevalence than those with intermediate body masses. The result that LV prevalence is also lower in heavier (i.e., older) animals suggests for the first time that LV infection is not persistent in rodents

Fevola, C.; Rossi, C.; Rosa', R.; Nordström, Å.; Ecke, F.; Magnusson, M.; Miller, A.L.; Niemimaa, J.; O. l. s. s. o. n., .G.E.; Jääskeläinen, A.J.; Hörnfeldt, B.; Henttonen, H.; Hauffe, H.C. (2017). Distribution and seasonal variation of Ljungan Virus in bank voles (Myodes glareolus) in Fennoscandia. JOURNAL OF WILDLIFE DISEASES, 53 (3): 552-560. doi: 10.7589/2016-06-145 handle: http://hdl.handle.net/10449/35951

Distribution and seasonal variation of Ljungan Virus in bank voles (Myodes glareolus) in Fennoscandia

Fevola, Cristina
Primo
;
Rossi, Chiara;Rosa', Roberto;Hauffe, Heidi Christine
Ultimo
2017-01-01

Abstract

Ljungan virus (LV) is a picornavirus originally isolated from Swedish bank voles (Myodes glareolus) in 1998. The association of LV with human disease has been debated ever since, but fundamental data on the ecology of the virus are still lacking. Here we present results of the first intensive study on the prevalence of LV in bank voles trapped in Fennoscandia (Sweden and Finland) from 2009–2012 as determined by PCR. Using an LV-specific RT-PCR, LV was detected in the liver of 73 out of 452 (16.2%) individuals and in 13 out of 17 sampling sites across Sweden and Finland (mean per site prevalence 16%, SE 3%, range 0–50%). We found more infected animals in autumn compared to spring, and lighter and heavier individuals had a higher prevalence than those with intermediate body masses. The result that LV prevalence is also lower in heavier (i.e., older) animals suggests for the first time that LV infection is not persistent in rodents
Finland
Parechovirus B
Prevalence
Picornavirus
Rodent-borne virus
RT-PCR
Sweden
Settore VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
2017
Fevola, C.; Rossi, C.; Rosa', R.; Nordström, Å.; Ecke, F.; Magnusson, M.; Miller, A.L.; Niemimaa, J.; O. l. s. s. o. n., .G.E.; Jääskeläinen, A.J.; Hörnfeldt, B.; Henttonen, H.; Hauffe, H.C. (2017). Distribution and seasonal variation of Ljungan Virus in bank voles (Myodes glareolus) in Fennoscandia. JOURNAL OF WILDLIFE DISEASES, 53 (3): 552-560. doi: 10.7589/2016-06-145 handle: http://hdl.handle.net/10449/35951
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