Ticks, as vectors of several notorious zoonotic pathogens, represent an important and increasing threat for human and animal health in Europe. Recent applications of new technology revealed the complexity of the tick microbiome, which may affect its vectorial capacity. Appreciation of these complex systems is expanding our understanding of tick-borne pathogens, leading us to evolve a more integrated view that embraces the 'pathobiome'; the pathogenic agent integrated within its abiotic and biotic environments. In this review, we will explore how this new vision will revolutionize our understanding of tick-borne diseases. We will discuss the implications in terms of future research approaches that will enable us to efficiently prevent and control the threat posed by ticks.

Vayssier Taussat, M.; Kazimirova, M.; Hubalek, Z.; Hornok, S.; Farkas, R.; Cosson, J.; Bonnet, S.; Vourch, G.; Gasqui, P.; Mihalca, A.D.; Plantard, O.; Silaghi, C.; Cutler, S.; Rizzoli, A. (2015). Emerging horizons for tick-borne pathogens: from the 'one pathogen-one disease' vision to the pathobiome paradigm. FUTURE MICROBIOLOGY, 10 (12): 2033-2043. doi: 10.2217/fmb.15.114 handle: http://hdl.handle.net/10449/27694

Emerging horizons for tick-borne pathogens: from the 'one pathogen-one disease' vision to the pathobiome paradigm

Rizzoli, Annapaola
2015-01-01

Abstract

Ticks, as vectors of several notorious zoonotic pathogens, represent an important and increasing threat for human and animal health in Europe. Recent applications of new technology revealed the complexity of the tick microbiome, which may affect its vectorial capacity. Appreciation of these complex systems is expanding our understanding of tick-borne pathogens, leading us to evolve a more integrated view that embraces the 'pathobiome'; the pathogenic agent integrated within its abiotic and biotic environments. In this review, we will explore how this new vision will revolutionize our understanding of tick-borne diseases. We will discuss the implications in terms of future research approaches that will enable us to efficiently prevent and control the threat posed by ticks.
Co-infections
Emerging diseases
Ixodes ricinus
New paradigm
Nextgeneration sequencing
Pathobiome
Unknown pathogens
Vector competence
Zoonoses
Settore VET/06 - PARASSITOLOGIA E MALATTIE PARASSITARIE DEGLI ANIMALI
2015
Vayssier Taussat, M.; Kazimirova, M.; Hubalek, Z.; Hornok, S.; Farkas, R.; Cosson, J.; Bonnet, S.; Vourch, G.; Gasqui, P.; Mihalca, A.D.; Plantard, O.; Silaghi, C.; Cutler, S.; Rizzoli, A. (2015). Emerging horizons for tick-borne pathogens: from the 'one pathogen-one disease' vision to the pathobiome paradigm. FUTURE MICROBIOLOGY, 10 (12): 2033-2043. doi: 10.2217/fmb.15.114 handle: http://hdl.handle.net/10449/27694
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/10449/27694
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