White spot syndrome virus (WSSV), the sole member of the monotypic family Nimaviridae, is considered an extremely lethal shrimp pathogen. Despite its impact, some essential biological characteristics related to WSSV genome dynamics, such as the synonymous codon usage pattern and selection pressure in genes, remain to be elucidated. The results show that compositional limitations and mutational pressure determine the codon usage bias and base composition in WSSV. Furthermore, different forces of selective pressure are acting across various regions of the WSSV genome. Finally, this study points out the possible occurrence of two major recombination events.

Sablok, G.; Sánchez Paz, A.; Wu, X.; Ranjan, J.; Kuo, J.; Bulla, I. (2012). Genome dynamics in three different geographical isolates of white spot syndrome virus (WSSV). ARCHIVES OF VIROLOGY, 157 (12): 2357-2362. doi: 10.1007/s00705-012-1395-7 handle: http://hdl.handle.net/10449/21281

Genome dynamics in three different geographical isolates of white spot syndrome virus (WSSV)

Sablok, Gaurav;Ranjan, Jayant;
2012-01-01

Abstract

White spot syndrome virus (WSSV), the sole member of the monotypic family Nimaviridae, is considered an extremely lethal shrimp pathogen. Despite its impact, some essential biological characteristics related to WSSV genome dynamics, such as the synonymous codon usage pattern and selection pressure in genes, remain to be elucidated. The results show that compositional limitations and mutational pressure determine the codon usage bias and base composition in WSSV. Furthermore, different forces of selective pressure are acting across various regions of the WSSV genome. Finally, this study points out the possible occurrence of two major recombination events.
Codon usage bias
Correspondence analysis
Gene expression level
White spot syndrome virus
Settore BIO/18 - GENETICA
2012
Sablok, G.; Sánchez Paz, A.; Wu, X.; Ranjan, J.; Kuo, J.; Bulla, I. (2012). Genome dynamics in three different geographical isolates of white spot syndrome virus (WSSV). ARCHIVES OF VIROLOGY, 157 (12): 2357-2362. doi: 10.1007/s00705-012-1395-7 handle: http://hdl.handle.net/10449/21281
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