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ItalianoOne important phase in drug development is to investigate distribution and delivery of therapeutic compounds to target organs identifying downstream associated metabolites. In tumors, one of the most important issues of pharmaceutical treatment is indeed the limited capability of chemotherapeutic drugs to penetrate tissues and reach all cells in a sufficient concentration inhibiting tumor growth. Mass-spectrometry imaging can be used to investigate the distribution of drugs, drug metabolites and metabolic indicators in the tumor microenvironment. However, to give pharmacologists a robust feedback on the efficacy of the different treatments, it is necessary to develop specific data analysis pipelines.
| Citation: | Prasad, M.; Giordano, S.; Morosi, L.; Davoli, E; Franceschi, P. (2015). Analyze drug distribution in tumors by MSI and image analysis. In: OurCon III: Imaging Mass Spectrometry Conference 2015, Calambrone, Pisa, Italy, October 27-29th, 2015. url: http://ourcon.org/ handle: http://hdl.handle.net/10449/28135 |
| Internal authors: | |
| Organization unit: | Computational Biology # CRI_2011-JAN2016 |
| Authors: | Prasad, M.; Giordano, S.; Morosi, L.; Davoli, E; Franceschi, P. |
| Title: | Analyze drug distribution in tumors by MSI and image analysis |
| Issue Date: | 2015 |
| Scientific Disciplinary Area: | Settore CHIM/01 - Chimica Analitica |
| Keywords ENG: | Mass spectrometry imaging Data Analysis |
| Keywords ITA: | Imaging con spettrometria di massa Analisi dati |
| Language: | English |
| Nature of content: | Abstract in Atti di convegno/Conference abstract |
| URL: | http://ourcon.org/ |
| Appears in Collections: | 03 - Conference object |
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| File | Description | Type | License | |
|---|---|---|---|---|
| PosterPrasad.pdf | Abstract | N/A | Tutti i diritti riservati (All rights reserved) | Utenti riconosciuti Request a copy |
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