Dobrava-Belgrade virus (DOBV)is considered the most pathogenic of hantaviruses in Europe, causing HFSR with case fatality rate up to 12%. The first DOBV strain was isolated from lungs of A. flavicollis mice captured in Slovenia, southeast Europe, and now represents the prototype DOBV strain (named Slovenia, or Slo/Af) from A. flavicollis. The spatial and temporal distribution of hantaviruses has been monitored in Trentino region ( northern Italy) since the year 2000 by performing seroprevalence studies in rodents and humans with IFAT. An intense long term serological monitoring of a population of Apodemus flavicollis has been carried out. During the period 2000 – 2008 the antibody seroprevalence of DOBV varied from 0% to 1.4% . From the year 2010 onwards a sudden increase has been registered: 3,8% in 2010, 3% in 2011 and 7,7% in 2012. Possible drivers affecting changes in DOBV seroprevalence in this rodent population will be discussed
Rizzoli, A.; Tagliapietra, V.; Rosa', R.; Hauffe, H.C.; Voutilainen, L.; Sironen, T.; Henttonen, H. (2013). Sudden increase in seroprevalence of Dobrava-Belgrade virus (DOBV) in the province of Trento, Italy. In: 5th European Congress of Virology (ECV), Lyon, September 11-14, 2013. url: http://goo.gl/34HwBe handle: http://hdl.handle.net/10449/23380
Sudden increase in seroprevalence of Dobrava-Belgrade virus (DOBV) in the province of Trento, Italy
Rizzoli, Annapaola;Tagliapietra, Valentina;Rosa', Roberto;Hauffe, Heidi Christine;
2013-01-01
Abstract
Dobrava-Belgrade virus (DOBV)is considered the most pathogenic of hantaviruses in Europe, causing HFSR with case fatality rate up to 12%. The first DOBV strain was isolated from lungs of A. flavicollis mice captured in Slovenia, southeast Europe, and now represents the prototype DOBV strain (named Slovenia, or Slo/Af) from A. flavicollis. The spatial and temporal distribution of hantaviruses has been monitored in Trentino region ( northern Italy) since the year 2000 by performing seroprevalence studies in rodents and humans with IFAT. An intense long term serological monitoring of a population of Apodemus flavicollis has been carried out. During the period 2000 – 2008 the antibody seroprevalence of DOBV varied from 0% to 1.4% . From the year 2010 onwards a sudden increase has been registered: 3,8% in 2010, 3% in 2011 and 7,7% in 2012. Possible drivers affecting changes in DOBV seroprevalence in this rodent population will be discussed
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