Mass Spectrometry Imaging allows for the study of the distribution of chemical compounds in tissue sections, opening-up possibilities of much more detailed understanding of biological processes. The size and complexity of the datasets, however, makes the data analysis phase challenging, in particular in the case of untargeted datasets. In this contribution we present a novel approach based on self-organizing maps for the analysis of untargeted imaging datasets. The key idea is to generate a shortlist of prototype images which represent the distribution of related ionic signals. The possibilities and advantages of the new approach are illustrated on an in-house data set of apple slices
Franceschi, P.; Wehrens, H.R.M.J. (2013). Self-organizing maps: a versatile tool for the automatic analysis of untargetedimaging datasets. In: F. Biasioli (editor), 3rd MS Food day, October 9-11, 2013, Trento. San Michele all'Adige (TN): Fondazione Edmund Mach: 297-298 (P.99). ISBN: 978-88-7843-035-8. handle: http://hdl.handle.net/10449/22792
Self-organizing maps: a versatile tool for the automatic analysis of untargeted imaging datasets
Franceschi, Pietro;Wehrens, Herman Ronald Maria Johan
2013-01-01
Abstract
Mass Spectrometry Imaging allows for the study of the distribution of chemical compounds in tissue sections, opening-up possibilities of much more detailed understanding of biological processes. The size and complexity of the datasets, however, makes the data analysis phase challenging, in particular in the case of untargeted datasets. In this contribution we present a novel approach based on self-organizing maps for the analysis of untargeted imaging datasets. The key idea is to generate a shortlist of prototype images which represent the distribution of related ionic signals. The possibilities and advantages of the new approach are illustrated on an in-house data set of apple slicesFile | Dimensione | Formato | |
---|---|---|---|
2013 MS Food Day 2013 297-298.pdf
non disponibili
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
1.28 MB
Formato
Adobe PDF
|
1.28 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.