Different strains of the same organism can share a large amount of their genetic material, the so called core pangenome. Nevertheless, these species can display different lifestyles and it is still not well known to what extent the core pangenome plays a role in the divergence of lifestyles between the two organisms. Here, we present a procedure for uncovering the conservation and divergence of gene expression by using large expression compendia. We will use data from two Salmonella enterica serovar Typhimurium strains as an example here, strain LT2 and strain 14028S, to assess if there are orthologous gene pairs with different expression domains related in both strains
Sonego, P.; Meysman, P.; Moretto, M.; Viola, R.; Laukens, K.; Cavalieri, D.; Engelen, K.A. (2015). Comparative analysis of gene expression: uncovering expression conservation and divergence between Salmonella enterica serovar Typhimurium strains LT2 and 14028S. In: Bacterial pangenomics: methods and protocols (editor(s) Mengoni, A.; Galardini, M.; Fondi, M.): Humana Press: 125-135. ISBN: 9781493917198 doi: 10.1007/978-1-4939-1720-4_8. handle: http://hdl.handle.net/10449/25071
Comparative analysis of gene expression: uncovering expression conservation and divergence between Salmonella enterica serovar Typhimurium strains LT2 and 14028S
Sonego, Paolo;Moretto, Marco;Viola, Roberto;Cavalieri, Duccio;Engelen, Kristof Arthur
2015-01-01
Abstract
Different strains of the same organism can share a large amount of their genetic material, the so called core pangenome. Nevertheless, these species can display different lifestyles and it is still not well known to what extent the core pangenome plays a role in the divergence of lifestyles between the two organisms. Here, we present a procedure for uncovering the conservation and divergence of gene expression by using large expression compendia. We will use data from two Salmonella enterica serovar Typhimurium strains as an example here, strain LT2 and strain 14028S, to assess if there are orthologous gene pairs with different expression domains related in both strainsFile | Dimensione | Formato | |
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